Pedicle Screw Fixation Study in Immature Porcine Spines to Improve Pullout Resistance during Animal Testing

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Pedicle Screw Fixation Study in Immature Porcine Spines to Improve Pullout Resistance during Animal Testing

The porcine model is frequently used during development and validation of new spinal devices, because of its likeness to the human spine. These spinal devices are frequently composed of pedicle screws with a reputation for stable fixation but which can suffer pullouts during preclinical implantation on young animals, leading to high morbidity. With a view to identifying the best choices to opti...

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Pedicle screw surface coatings improve fixation in nonfusion spinal constructs.

STUDY DESIGN Biomechanical and histologic analysis. OBJECTIVE To compare the strength of the bone-screw interface of standard uncoated pedicle screws with screws treated with hydroxyapatite (HA), titanium plasma spray (TPS), and a composite HA-TPS coating. SUMMARY OF BACKGROUND DATA Transpedicular screw fixation has become the gold standard in the treatment of various thoracolumbar spinal c...

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Pedicle screw fixation in the spine.

In August 1993, in the USA, an FDA advisory committee of experts reviewed the scientific data on pedicle screws and decided that not enough was known about the shortterm problems or the long-term safety and effectiveness of these devices to allow their use to be approved. Manufacturers were therefore forbidden to promote the use of screws in the spine, and patients were warned that pedicle scre...

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Unilateral Pedicle Screw Fixation with Bone Graft vs. Bilateral Pedicle Screw Fixation with Bone Graft or Cage: A Comparative Study.

BACKGROUND The aim of this study was to explore the clinical efficacy of unilateral pedicle screw fixation with bone graft (UPSFB) in treating single-segment lumbar degenerative diseases (LDD), as compared to bilateral pedicle screw fixation with bone graft (BPSFB) or with cage (BPSFC). MATERIAL/METHODS Medical records were retrospectively collected between 01/2010 and 02/2015 in Longyao Coun...

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Biomechanical Analysis of a Pedicle Screw-Rod System with a Novel Cross-Link Configuration

STUDY DESIGN The strength effects of a pedicle screw-rod system supplemented with a novel cross-link configuration were biomechanically evaluated in porcine spines. PURPOSE To assess the biomechanical differences between a conventional cross-link pedicle screw-rod system versus a novel cross-link instrumentation, and to determine the effect of the cross-links. OVERVIEW OF LITERATURE Transve...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2015

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0127463